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The presented HEK 293T cell experiments showed that the SCX/pS-MIP enrichment approach resulted in a larger number of phosphopeptides (924) compared with the TiO 2 approach (711) while using 10-fold less peptide sample

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However, the drug can also be modified via phase I metabolism, producing NAPQI, a highly toxic metabolite which is then processed via phase II metabolism to a non-toxic product by the addition of cysteine in a manner dependent on glutathione (Figure 3)

Crucially, the promotion of infection by SsCm1 depends entirely on MORF2s, and the virulence function of SsCm1 is lost after silencing or losing MORF2s , which further emphasizes that MORF2s are the physiological targets of SsCm1