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The compound's ability to act on dopaminergic and serotonergic pathways extends its repair activity into the nervous system, reflecting the multi-layered mechanism behind how BPC-157 works

Aggarwal B, Swisher SG , Hunt K, Jr P, JB, Ajani J, Komaki RR, Molke KL, Lehman J, Bismark M, Walsh GL, Correa AM, Ho L, Liao Z, Lynch P, Rice D, Smythe WR, Stevens C, Vaporciyan AA, Yao J, Roth JA

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Our findings showed that liver-specific Gclc deletion results in increased Nrf2 activity, impaired expression of lipogenic enzymes, and decreased circulating triglycerides