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Retatrutide is a triple hormone receptor agonist, acting on three receptors simultaneously: GLP-1 (glucagon-like peptide-1) reduces appetite and slows gastric emptying GIP (glucose-dependent insulinotropic polypeptide) enhances insulin secretion and may improve fat metabolism Glucagon receptor increases energy expenditure and promotes fat breakdown It is worth noting that glucagon receptor agonism can, in isolation, raise blood glucose levels

To learn more, see How long does it take for Zepbound to work?" Do you regain weight after stopping tirzepatide